Clinicopathological features of melanocytic nevi and their correlation to cutaneous melanoma among patients attending King Abdulaziz University Hospital, Jeddah, Saudi Arabia
DOI:
https://doi.org/10.52981/sjms.v13i2.1085Keywords:
cutaneous, melanocytic,, intradermal,, congenital melanomaAbstract
Melanocytic nevi (MN) pose diagnostic difficulty due to their heterogeneous clinical,
biological and molecular characteristics. Their recognition is also important because
cutaneous melanomas are known to arise in pre-existing MN. Aim: This retrospective
study aims to examine the clinical features and histopathological types of MN among
patients attending King Abdulaziz University Hospital between January 2000 and
December 2017. It also aims to examine the correlation of their number to cutaneous
melanoma. Materials and Methods: All biopsy specimen data of pigmented skin
lesions were collected through an electronic search of the Anatomic Pathology
archives. Age, gender and site distribution and histological features were studied
for different MN and their relation to cutaneous melanoma if associated. Results:
MN were most common in the third decade of life affecting females more than
males. The most frequent anatomic location was the head region, 176 (45.3%), with
face being most frequent site, 45 (25.5%). Histologically the most common MN was
intradermal type accounting for 217 (56%). Two dysplastic nevi and one congenital
nevus was associated with cutaneous melanoma. Conclusion: MN most commonly
affected patients in their third decade of life .Females were more affected than males.
Histologically most MN were of intradermal type and were rarely associated with
cutaneous melanoma.
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[31] Ross, A. L., Sanchez, M. I., and Grichnik, J. M. (2011). Molecular nevogenesis.Dermatology Research and Practice, 2011:463184. DOI: 10.1155/2011/463184.
[32] Al Hawsawi, K., Al Zahrani, B., Bamani, S., et al. (2016). Acquired melanocytic nevus:An unusual case presentation. The Open Dermatology Journal, vol. 1, no. 1, pp. 6-8.
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2021-08-20
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