Isolation, Identification and Antimicrobial Activity of a Flavone from the leaves of Cassia obtusifolia.
Keywords:
Flavonoids, Isolation, Cassia obtusifolia, Bacillus subtilis
Abstract
Flavonoids are polyphenol compounds possess antioxidant, anti-inflammatory, anti-allergic, hepato protective, anti-thrombotic, anti-carcinogenic and ant-diabetic activity, occur commonly in plants such Cassia obtusifolia. The powdered leaves of Cassia obtusifolia was extracted with ethanol solvent. The ethanolic extract was phytochemicaly screened and Chromatographic fractionations of the ethanolic extract gave compound I. The structure of this compound was deduced on the basis of its IR, UV,1H NMR and MS. Compound 1was screened for its antimicrobial activity and the results were exhibited activity against all tested organisms except for Bacillus subtilis.
References
Anon, K., (1980): “Poisonous Plant of Southern U.S. “The Cooperative Extention Service, University of Georgia College of Agriculture, Pamphet, and P30.
Anon K., (1982). “Medical and Aromatic Plant of the Sudan" Kartoum Trading and Project Company, Khartoum, Sudan, Pamphet.p40.
Avtar C., Bhawna G., (2019): Chemistry and Pharmacology of Flavonoids- A Review: Indian J. of Pharmaceutical Education and Research, 53(1), 8-20. Bors, W., Heller, W., Michel. C., Saran, M., Methods Enzymol. 186,343
Catherine, A., Rice, E., (2003): “Flavonoids in Health and Disease”Marcel Dekker, New York, 2 nd Ed., p 43.
Colerige, Smith, PO. Thomas, P., Scurr, J., H., Dormandy, J., A., Br., (1980). Med., J; 296:1726, 7.
Dirar, H.A., (1984): “Kawal; Meat Substitute from Fermented Cassia obtusifolia leaves” Economic Botany, 38,342.
El Tahir, A., Satti, G. M. H. and Khalid, S. A., (1999): J. Ethnopharmacol., 64, 233.
Hegarty, V.M., May, H.M., Khaw, K.T., (2000): Am. J Clin Nutr., 71, 1003.
Hif, CS., Howell. SL. (2007), J. Amer. Coll. Nutr. , 26, 5 471.
Mamman A. and Isa M. A., (2013): Pythochemical and antibacterial activity of leaves extracts Guiera Senegalesis L. on selected species of Gram positive and Gram negative Bacteria, 2, (1), 262-268.
Jaísa O., Mariana C., Laise C., Daniel L., Paulo C., Ana P., Tânia F., Mercedes V.,Ana V., Gerardo F.,and Mauricio A.,(2020): Extraction of Flavonoids From Natural Sources Using Modern Techniques. Frontiers in Chemistry, 8, 1-15, doi: 10.3389/fchem.2020.507887.
Kayser, O., Abreu, P. M., (2001): Pharmaceutical Biology, 39(4), 288.
Khare, C.P., Janak Puri, (2007): “Indian Medicinal Plants” Springer – Verlag, New York, p47.
Lukacin, R. A.L., (2003): Phytochemistry, 62, 287.
Maria C., Diana C., Artur M., (2021): Plant Flavonoids: Chemical Characteristics and Biological Activity, Molecules, 26, 5377. https://doi.org/10.3390/molecules26175377
Md Y., Seongkyu P., Munseog C., (2021): Phytochemistry, Ethno pharmacological Uses, Biological Activities, and Therapeutic Applications of Cassia obtusifolia L.: A Comprehensive Review, Molecules, 26, 6252. https://doi.org/10.3390 /molecules26206252
Ousman, A., Ngassoun, M., and kanga. (2005): .J. Food Technolog, 76, 96.
Sapna I, Kamaljit M, Priya R, Jayadeep PA. (2019): Milling and thermal treatment induced changes on phenolic components and antioxidant activities of pigmented rice flours.J. of food science and technology. 56(1):273-80.
Satyajit, D., Sarker, Zahid ,L. A.,lexander, I., “ Natural Products Isolation” Humana Press , 2 nd Ed.,p252 (2006).
Scarano, A., Chieppa, M., and Santino, A. (2018). Looking at flavonoid biodiversity in horticultural crops: a colored mine with nutritional benefits. Plants 7:E98. Doi: 10.3390/plants7040098
Tawel, M.M.A., (2003): “Effect of Processing on in vitro Protein Digestibility and Anti-nutritional Factor of Chickpea”. M. Sc. Thesis, University of Khartoum, Sudan.
Tubiana, E., (1977): "The Zaghaea from an Ecological Perspective” A.A.A.Keniam, Sudan, p26.
Anon K., (1982). “Medical and Aromatic Plant of the Sudan" Kartoum Trading and Project Company, Khartoum, Sudan, Pamphet.p40.
Avtar C., Bhawna G., (2019): Chemistry and Pharmacology of Flavonoids- A Review: Indian J. of Pharmaceutical Education and Research, 53(1), 8-20. Bors, W., Heller, W., Michel. C., Saran, M., Methods Enzymol. 186,343
Catherine, A., Rice, E., (2003): “Flavonoids in Health and Disease”Marcel Dekker, New York, 2 nd Ed., p 43.
Colerige, Smith, PO. Thomas, P., Scurr, J., H., Dormandy, J., A., Br., (1980). Med., J; 296:1726, 7.
Dirar, H.A., (1984): “Kawal; Meat Substitute from Fermented Cassia obtusifolia leaves” Economic Botany, 38,342.
El Tahir, A., Satti, G. M. H. and Khalid, S. A., (1999): J. Ethnopharmacol., 64, 233.
Hegarty, V.M., May, H.M., Khaw, K.T., (2000): Am. J Clin Nutr., 71, 1003.
Hif, CS., Howell. SL. (2007), J. Amer. Coll. Nutr. , 26, 5 471.
Mamman A. and Isa M. A., (2013): Pythochemical and antibacterial activity of leaves extracts Guiera Senegalesis L. on selected species of Gram positive and Gram negative Bacteria, 2, (1), 262-268.
Jaísa O., Mariana C., Laise C., Daniel L., Paulo C., Ana P., Tânia F., Mercedes V.,Ana V., Gerardo F.,and Mauricio A.,(2020): Extraction of Flavonoids From Natural Sources Using Modern Techniques. Frontiers in Chemistry, 8, 1-15, doi: 10.3389/fchem.2020.507887.
Kayser, O., Abreu, P. M., (2001): Pharmaceutical Biology, 39(4), 288.
Khare, C.P., Janak Puri, (2007): “Indian Medicinal Plants” Springer – Verlag, New York, p47.
Lukacin, R. A.L., (2003): Phytochemistry, 62, 287.
Maria C., Diana C., Artur M., (2021): Plant Flavonoids: Chemical Characteristics and Biological Activity, Molecules, 26, 5377. https://doi.org/10.3390/molecules26175377
Md Y., Seongkyu P., Munseog C., (2021): Phytochemistry, Ethno pharmacological Uses, Biological Activities, and Therapeutic Applications of Cassia obtusifolia L.: A Comprehensive Review, Molecules, 26, 6252. https://doi.org/10.3390 /molecules26206252
Ousman, A., Ngassoun, M., and kanga. (2005): .J. Food Technolog, 76, 96.
Sapna I, Kamaljit M, Priya R, Jayadeep PA. (2019): Milling and thermal treatment induced changes on phenolic components and antioxidant activities of pigmented rice flours.J. of food science and technology. 56(1):273-80.
Satyajit, D., Sarker, Zahid ,L. A.,lexander, I., “ Natural Products Isolation” Humana Press , 2 nd Ed.,p252 (2006).
Scarano, A., Chieppa, M., and Santino, A. (2018). Looking at flavonoid biodiversity in horticultural crops: a colored mine with nutritional benefits. Plants 7:E98. Doi: 10.3390/plants7040098
Tawel, M.M.A., (2003): “Effect of Processing on in vitro Protein Digestibility and Anti-nutritional Factor of Chickpea”. M. Sc. Thesis, University of Khartoum, Sudan.
Tubiana, E., (1977): "The Zaghaea from an Ecological Perspective” A.A.A.Keniam, Sudan, p26.
Published
2022-12-28
Section
Articles
