Antimicrobial potential of Prosopis chilensis Against Some Causative Agents of Urogenital Infections.

  • Mishkat Soluman Rokza
Keywords: Antimicrobial potential; Prosopis chilensis; leaves extract; Fruits extract; Antifungal activity.


 Medicinal plants have been used internationally and globally as traditional remedies for numerous human illnesses for thousands of years till now. This study was aimed to investigate and compare the antimicrobial properties of leaves and fruits extract of Prosopis chilensis against standard strains and clinical isolates. Antimicrobial activities were detected by the agar well diffusion method and the broth dilution method. The mean diameter of inhibition zones were analyzed statistically using One- Way analysis of variance using SPSS Version (20). Leaves and fruits methanol extracts exhibited antimicrobial potential against standard strains viz: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus vulgaris, and Candida albicans with zones of inhibition   ranged from 17 mm to 28 mm. The minimum inhibitory concentration (MIC) showed by leaves and fruits methanol extracts on the standard bacteria was ranged from 12.50 mg/ml to 100 mg/ml and the minimum bactericidal concentration (MBC) was ranged from 25 mg/ml to 100 mg/ml. On the other hand, the MIC of methanol leaves extracts toward standard fungi was ranged from 50 to 100 mg/ml, while the minimum fungicidal concentration (MFC) was ranged from 100 to > 100 mg/ml. Leaves methanol extract revealed significant antimicrobial activity on the clinical isolates The MIC exhibited by this extract on clinical bacterial isolates was ranged from 12.50 mg/ml to 100 mg/ml and the MBC was ranged from 25 mg/ml to >100 mg/ml. The MIC from the same extract toward clinical isolates of Candida albicans was ranged from 12.50 mg/ml to 25 mg/ml, whereas the MFC was ranged from 25 mg/ml to 50 mg/ml. The study concluded that the methanolic extracts of the mesquite plant contain antimicrobial agents, which proved to be effective against both standard strains and clinical isolates.


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