Association of Age, Gender, and HO-1 T(-413)A Polymorphism with COVID-19 Severity in a Sudanese Population

المؤلفون

  • Mai Shakir Haridy, Ozaz Y.M. Ahmed, Mustafa Ibrahim Abbas, Khalid Abdelsamea Mohamedahmed, Bakri Y. M. Nour, Yasmin Abdo Modawi Ebaid, Samar Ibn Omer Abdalrahman Alsharif, Adil Mergani

الكلمات المفتاحية:

COVID-19, Heme Oxygenase-1, Genetic Polymorphism, Disease Severity, Sudan

الملخص

ackground: COVID-19 severity varies widely among individuals, influenced by age, gender, and genetic predisposition. The heme oxygenase-1 (HO-1) T(-413)A promoter polymorphism has been implicated in modulating inflammatory and oxidative-stress responses and may influence disease outcomes, but data from Sudanese and other African populations remain scarce.

Objectives: This study aimed to evaluate the association of age, gender, and the HO-1 T(-413)A polymorphism with COVID-19 severity among Sudanese patients.

التنزيلات

منشور

2026-09-18

كيفية الاقتباس

Adil Mergani, M. S. H. O. Y. A. M. I. A. K. A. M. B. Y. M. N. Y. A. M. E. S. I. O. A. A. . (2026). Association of Age, Gender, and HO-1 T(-413)A Polymorphism with COVID-19 Severity in a Sudanese Population. Journal of Omdurman Islamic University Applied Sciences, 22(3), 265–279. استرجع في من https://journal.oiu.edu.sd/oiujas/article/view/3815

إصدار

مجلد 22 عدد 3 (2026): مجلة جامعة أم درمان الإسلامية (م ج أ أ)، للعلوم التطبيقية : ISSN: 3122-5640

القسم

المقالات