Evaluation of Serum Uric Acid Level among Sudanese Obese Subjects

Rabie Elagib  Abdallah; Mojahid Babiker  Hamza; Mohamed Malik  Mohamed; Mostafa Mohamed Ibrahim; Monieb Mohamed  Abdalla; Fadlalla Mohamed  Elgaoda; GadAllah  Modawe

doi:10.52981/smlj.v10i1.2771

Rabie Elagib Abdallah 1. Department of Clinical Chemistry, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Sudan
Mojahid Babiker Hamza Department of Clinical Chemistry, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Sudan
Mohamed Malik Mohamed Department of Clinical Chemistry, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Sudan
Mostafa Mohamed Ibrahim Department of Clinical Chemistry, Faculty of Medical Laboratory Sciences, Omdurman Isl
Monieb Mohamed Abdalla Department of Clinical Chemistry, Faculty of Medical Laboratory Sciences, Omdurman Isl
Fadlalla Mohamed Elgaoda Department of Clinical Chemistry, Faculty of Medical Laboratory Sciences, Omdurman Isl
GadAllah Modawe 1. Department of Biochemistry, Faculty of Medicine and Health Sciences, Omdurman Islamic University, Sudan.

DOI: https://doi.org/10.52981/smlj.v10i1.2771

Keywords: uric acid, obese, cardio disease, hypertension, hyperuricemia

Abstract

Background: Besides gout, elevated uric acid level is related to a variety of other conditions including increase alcohol and purine rich food consumption and obesity. Hyperuricemia is considered to be a considered to be a common lifestyle disorder related with obesity.

Objectives: To evaluate serum uric acid level in Sudanese obese subjects.

Materials and Methods: Analytical case control study conducted at Khartoum state during the period from July to August 2021. Fifty obese subjects as a case group and 50 as a control groups . Uric acid level was assayed using spectrophotometer. The data analyzed using SPSS version ( 25).

Results: The serum uric acid and BMI in obese is a significantly higher than non obese with p value = 0.000. In obese group show mean uric acid concentration of males is significantly higher than females (p< 0.05). The risk of developing CVD is 8 time higher in obese subjects with high uric acid levels. Serum uric acid level showed strong significant positive correlation with BMI(r=0.79, p= 0.000), and no correlated with age (r=0.03, p= 0.7).

Conclusion: The obese had a significantly higher of serum uric acid. The elevation of uric acid level is sex dependent and is positively correlation with BMI.

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