Chlamydia trachomatis IgM antibodies among women suffering infertility in Gezira State, Sudan

  • Hajir Mohammed Hussien Omer 1. Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, University of Gezira, Sudan
  • Khalid Eltahir Khalid Khieralla 2. Department of Basic Medical Sciences, Faculty of Applied Medical Sciences, Albaha University, Saudi Arabia
  • Abdulazeem Abdulsalam Ibrahim Alkhidir Omdurman Islamic University, Faculty of Medical laboratory sciences, Sudan
  • Mohammed Abdelssalam Hassan 3. Department of Immunology, Faculty of Medical Laboratory Science, Omdurman Islamic University, Sudan
Keywords: Chlamydia trachomatis, Primary Infertility, Secondary Infertility, Symptoms

Abstract

Background:

Although the symptoms of genital chlamydia infection vary from symptomatic to asymptomatic, it has a profound impact on the female reproductive system causing ascending infections which may lead to infertility. We aimed to detect the genital chlamydia infection and common associated symptoms in both primary and secondary infertility cases.

Methods:

One hundred and sixty two Sudanese women suffering infertility were recruited to this study. Blood samples were collected from each woman, and then the separated serum was tested for the presence of anti-chlamydia trachomatis IgM using ELISA technique. A designed questionnaire was used to collect demographic and clinical presentation.

Results:

The percentage of chlamydia infection was 48.6% among women suffering primary infertility and 81.8% among those suffering secondary infertility with significant differences between the two groups (p value 0.00). Women with secondary infertility exhibited significantly more common chlamydia symptoms than those with primary infertility. Chlamydia infection was significantly associated with the age, burning in urination and urethritis (p value <0.05).

Conclusions:

Secondary infertile women affected by chlamydia infection and symptoms more than women those have primary infertility. Screening for chlamydia infection is mandatory.

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Published
2022-10-30