A case of conjunctivitis following mild illness COVD-19 infection
Keywords:
COVD-19, Conjunctivitis, mild illness
Abstract
Background
Up to date, COVID-19 resulted in nearly 4 million deaths worldwide, making it the most serious global health disaster in hundred years [1]. Previously, there were multiple anecdotal and published reports of eye redness and irritation in COVID-19 patients, implicating conjunctivitis as an ocular presentation of the infection. COVID-19 has been linked to multiple ophthalmic illness, according to new research, but most of literature links the pandemic to Conjunctivitis as a common encounter escorting respiratory findings [2]. The authors here report a case of mild illness COVID-19 that developed conjunctivitis a week after being diagnosed with the illness.
Summary
In this case report, a 40 years male presented with mild symptoms of COVID-19 which proved to be positive. Six days later, he developed redness in his right eye, which was associated with mild pain and itching. The left eye acquired the same symptoms within 24 hours. Conservative management was given in the form of antihistamine eye drop which was prescribed two times daily. A diagnosis of COVID-19 associated conjunctivitis was issued, which is uncommon to be associated with mild COVID.
References
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19. Xia J, Tong J, Liu M, Shen Y, Guo D. Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection. J Med Virol. 2020 Jun;92(6):589-594. doi: 10.1002/jmv.25725. Epub 2020 Mar 12. PMID: 32100876; PMCID: PMC7228294.
20. Kumar K, Prakash AA, Gangasagara SB, Rathod SBL, Ravi K, Rangaiah A, Shankar SM, Basawarajappa SG, Bhushan S, Neeraja TG, Khandenahalli S, Swetha M, Gupta P, Sampritha UC, Prasad GNS, Jayanthi CR. Presence of viral RNA of SARS-CoV-2 in conjunctival swab specimens of COVID-19 patients. Indian J Ophthalmol. 2020 Jun; 68 (6):1015-1017.doi:10.4103/ijo.IJO_1287_20. PMID:32461418;PMCID:PMC7508154.
2. Hu K, Patel J, Swiston C, et al. Ophthalmic Manifestations of Coronavirus (COVID-19) [Updated 2022 Jan 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK556093 /
3. Clinical Spectrum of SARS-CoV-2 Infection. In: COVID-19 Treatment Guidelines Panel. Coronavirus Disease 2019 (COVID-19) Treatment Guidelines [Internet]. National Institutes of Health (Page 48). Available at: https://www.covid19treatmentguidelines.nih.gov /. Accessed [12 February 2022].
4. Sindhuja K, Lomi N, Asif MI, Tandon R. Clinical profile and prevalence of conjunctivitis in mild COVID-19 patients in a tertiary care COVID-19 hospital: A retrospective cross-sectional study. Indian J Ophthalmol. 2020 Aug; 68(8): 1546–1550. doi: 10.4103/ijo.IJO_1319_20
5. Al-Namaeh M. COVID-19 and conjunctivitis: a meta-analysis. Ther Adv Ophthalmol. 2021 Jan - Dec; 13: 25158414211003368. doi:10.1177/ 25158414211003368
6. Salducci M, La Torre G. COVID-19 emergency in the cruise's ship: a case report of conjunctivitis. Clin Ter. 2020 May-Jun; 171(3):e189-e191.doi:10.7417/CT.2020. 2212. PMID: 32323704.
7. Navel V, Chiambaretta F, Dutheil F. Haemorr- hagic conjunctivitis with pseudomembranous related to SARS-CoV-2. Am J Ophthalmol Case Rep. 2020 Sep; 19: 100735. doi: 10.1016/j.ajoc.2020.100735
8. Loffredo L, Pacella F, Pacella E, Tiscione G, Oliva A, Violi F. Conjunctivitis and COVID‐
9. 19: A meta‐analysis. J Med Virol. 2020 May 22:10.1002/jmv.25938.doi:10.1002/jmv.25938 [Epub ahead of print].Güemes-Villahoz N, Burgos-Blasco B, García-Feijoó J, Sáenz-Francés F, Arriola-Villalobos P, Martinez-de-la-Casa JM, Benítez-Del-Castillo JM, Herrera de la Muela M. Conjunctivitis in COVID-19 patients: frequency and clinical presentation. Graefes Arch Clin Exp Ophthalmol. 2020 Nov;258(11):2501-2507 doi:10.1007/s00417-020-04916-0. Epub 2020 Aug 29. PMID: 32860573; PMCID: PMC7455778.
10. Xuejie L, Ming W, Jing D, Wenjun W, Yanning Y, Wei J. Novel coronavirus disease with conjunctivitis and conjunctivitis as first symptom: Two cases report. Chinese J Exp Ophth. 2020; 38(4): 318-321. DOI: 10.3760/cma.j.cn115989-20200303-00133
11. Daruich A, Martin D, Bremond-Gignac D. Unilateral conjunctivitis as first presentation of Coronavirus Disease 2019 (COVID-19): A telemedicine diagnosis. J Fr Ophtalmol. 2020 May;43(5):e167–e168.doi:10.1016/j.jfo.2020 .04.001
12. Marquezan MC, Marquezam JP, Nascimento H, Chalita MR, de Freitas D, Belfort R Jr. Conjunctivitis Related to not Severe COVID-19: A Case Report. Ocul Immunol Inflamm. 2021 May 19; 29(4):631-633. doi: 10.1080/09273948.2020.1837186. Epub 2020 Nov 20. PMID: 33215962.
13. Scalinci SZ, Battagliola ET. Conjunctivitis can be the only presenting sign and symptom of COVID-19. ID Cases. 2020; 20: e00774. https://doi.org/10.1016/j.idcr.2020.e00774
14. Alrawashdeh HM, Al Zubi K, Abdulmannan DM, Al-Habahbeh O, Abu-Ismail L. Conjunctivitis can be the only sign and symptom of COVID-19 in some patients. Qatar Med J. 2021; 2021(2): 31. doi: 10.5339/qmj.2021.31
15. Mocanu V, Bhagwani D, Sharma A, Borza C, Rosca CI, Stelian M, Bhagwani S, Marusiac Haidar L, Kshtriya L, Kundnani NR, Horhat FR, Horhat R. COVID-19 AND THE human eye - conjunctivitis a lone covid-19 finding - A case-control study. Med Princ Pract. 2022 Jan 5. doi: 10.1159/000521808. Epub ahead of print. PMID: 34986482.
16. Ozturker ZK. Conjunctivitis as sole symptom of COVID-19: A case report and review of literature. Eur J Ophthalmol. 2020 Jul 24: 1120672120946287.doi:10.1177/11206721209 46287
17. Wu P, Liang L, Chen CB, Nie SQ. A child confirmed COVID-19 with only symptoms of conjunctivitis and eyelid dermatitis. Graefes Arch Clin Exp Ophthalmol. 2020 Apr 24: 1–2. doi: 10.1007/s00417-020-04708-6
18. Nayak B, Poddar C, Panigrahi MK, Tripathy S, Mishra B. Late manifestation of follicular conjunctivitis in ventilated patient following COVID-19 positive severe pneumonia. Indian J Ophthalmol. 2020 Aug; 68(8): 1675–1677. doi: 10.4103/ijo.IJO_1682_20
19. Xia J, Tong J, Liu M, Shen Y, Guo D. Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection. J Med Virol. 2020 Jun;92(6):589-594. doi: 10.1002/jmv.25725. Epub 2020 Mar 12. PMID: 32100876; PMCID: PMC7228294.
20. Kumar K, Prakash AA, Gangasagara SB, Rathod SBL, Ravi K, Rangaiah A, Shankar SM, Basawarajappa SG, Bhushan S, Neeraja TG, Khandenahalli S, Swetha M, Gupta P, Sampritha UC, Prasad GNS, Jayanthi CR. Presence of viral RNA of SARS-CoV-2 in conjunctival swab specimens of COVID-19 patients. Indian J Ophthalmol. 2020 Jun; 68 (6):1015-1017.doi:10.4103/ijo.IJO_1287_20. PMID:32461418;PMCID:PMC7508154.
Published
2022-10-30
Section
Articles
