Effect of ethanolic extract of croton zambesicus fruit on some biochemical parameters

  • Shazalia abdallah Mohamed hemit Department of Science University of science and technology- Sudan
  • Hateil Elkamali Department of botany faculty of science and technology Omdurman Islamic university- Sudan
  • Elmuaiz Gasmalbari Department of Biochemistry Faculty of Medicine Omdurman Islamic University- Sudan
  • Abdelsamee Elobeid Department of Clinical chemistry Faculty of Medical Laboratory Science , Omdurman Islamic University- Sudan
Keywords: ethanolic extraction, croton zambesicus, biochemical parameters

Abstract

This current study aimed to evaluate the C. zambesius extracts were harvested in Sudan, on biochemical parameters (Glucose, total protein, albumin, triglyceride, cholesterol, urea, and creatinine, ALT, AST and ALP) and toxic effects in albino male rats compared to representing control.

Thirty five    male albino rats with initial weights ranging from 100-150 g were used in this study. Ethanol 70% for 72 hours at room temperature with occasional shaking and prepared extract was used for the various tests. Rats plasma were tested for biochemical parameters. The data were subjected to one –way analysis of variance (ANOVA).

Different groups were treated with ethanolic extract.

Glucose, T. protein, AST and ALT they were increased in experimental group B 1 while the remainders they were decreased. In experimental group C 1 Glucose, T. protein, Albumin and AST    they were increased, the remainders were decreased.  In experimental group D 1 Glucose, T. protein, Albumin, AST, ALT, and ALP they were increased, while the remainders they were decreased.

In experimental group B2 all parameters they were decreased, except AST it was increased.  Albumin, triglycerides, creatinine, ALT and ALP in the group C2 were decreased, while Glucose, T. protein, Urea and AST were increased. Cholesterol, AST, ALT and ALP in the group D2 were increased, while Glucose, T. protein, triglycerides, urea and creatinine were decreased.

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Published
2022-10-31