Frequency of urinary tract infection among cancer patients receiving the chemotherapeutic drug at radiation and isotopes center of Khartoum (RICK)

Mahjoob Osman  Mahjoob; Asma  Ibrahim   Ahmed; Amani Adam  Mohammed; Eman Siddig   Mohammed; Hadeel Aljaili  Altyeb; Hend  Suliman  Omer; Yageen Babiker  Ahmed

doi:10.52981/smlj.v10i2.2855

Mahjoob Osman Mahjoob Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Omdurman, Sudan
Asma Ibrahim Ahmed Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Omdurman, Sudan
Amani Adam Mohammed Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Omdurman, Sudan
Eman Siddig Mohammed Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Omdurman, Sudan
Hadeel Aljaili Altyeb Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Omdurman, Sudan
Hend Suliman Omer Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Omdurman, Sudan
Yageen Babiker Ahmed Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Omdurman, Sudan

DOI: https://doi.org/10.52981/smlj.v10i2.2855

Keywords: UTI, chemotherapeutic drug, RICK

Abstract

Background: Chemotherapy often decreases the number of white blood cells in the body. White blood cells fight bacterial, fungal, and viral infections. Neutropenic patients, usually have their course of treatment interrupted and stopped unless blood cells return to normal. Despite the presence of infection, the burden and causes of this are not known.

Aims: Assess the risk of urinary tract infection among cancer patients receiving a chemotherapeutic drug. Also, evaluation of antibiotics used for treatment and the incidence of infection in males and females and among children

Methods: Fifty midstream urine (MSU) specimens were collected from patients who undergo chemotherapy treatment then specimens were analyzed to isolate bacterial pathogens, and evaluate antibiotics used for treatment.

Results: Out of 50 urine specimens investigated, 23 different isolates were recovered giving a percentage of (46%), and 27 urine specimens (54%) showed no growth. S. aureus (26.1%) followed by E.coli (21.7%), S. epidermidis (17.4%), K. pneumoniae (13%), p. mirabilis (13%), and Ps. aeruginosa (8.7%).

Conclusion: The most frequent isolate is S. aureus and E.coli. Females and adults were more infected than males and children respectively.

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