Desmoplastic Infantile Astrocytoma in a 47-day Old Male Infant with Four-year Follow-up: A Rare Case Report and Literature Review
Keywords:
brain neoplasm, astrocytoma, pediatric neurosurgery, oncology, desmoplastic cerebral astrocytoma of infancy, desmoplastic infantile ganglioglioma
Abstract
Desmoplastic infantile astrocytoma/ganglioglioma (DIA/DIG) is a rare mixed neuronalglial solid cystic brain tumor found in infantile cerebral hemispheres. The main
presentation of the tumor is the rapidly enlarging of the head circumference with
hydrocephalus and seizure. DIA is classified as a WHO Grade 1 brain tumor but, due
to the rarity of the tumor, few studies are available on tumor survival and prognosis.
Herein, we report a 47-day-old male infant diagnosed with DIA and the four-year
follow-up.
References
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Organization classification of tumors of the central nervous system: A summary.
Acta Neuropathologica, vol. 131, no. 6, pp. 803–820.
[4] Tan�k, C., Devecioğlu, E. G., Hasçiçek, S., et al. (2018). A rare tumor in childhood
desmoplastic infantile astrocytoma: two case reports. The Medical Bulletin of Sisli
Etfal Hospital, vol. 52, no. 3, pp. 224–228.
[5] Taratuto, A. L., Monges, J., Lylyk, P., et al. (1984). Superficial cerebral astrocytoma
attached to dura. Report of six cases in infants. Cancer, vol. 54, pp. 2505–2512.
[6] Alexiou, G. A., Stefanaki, K., Sfakianos, G., et al. (2008). Desmoplastic infantile
ganglioglioma: A report of 2 cases and a review of the literature. Pediatric
Neurosurgery, vol. 44, no. 5, pp. 422–425.
[7] Bianchi, F., Tamburrini, G., Massimi, L., et al. (2016). Supratentorial tumors typical of
the infantile age: Desmoplastic infantile ganglioglioma (DIG) and astrocytoma (DIA).
A review. Child’s Nervous System, vol. 32, no. 10, pp. 1833–1838.
[8] Bader, A., Heran, M., Dunham, C., et al. (2015). Radiological features of infantile
glioblastoma and desmoplastic infantile tumors: British Columbia’s Children’s
Hospital experience. Journal of Neurosurgery, vol. 16, no. 2, pp. 119–125.
[9] Darwish, B., Arbuckle, S., Kellie, S., et al. (2007). Desmoplastic infantile
ganglioglioma/astrocytoma with cerebrospinal metastasis. Journal of Clinical
Neuroscience, vol. 14, no. 5, pp. 498–501.
[10] Samkari, A., Alzahrani, F., Almehdar, A., et al. (2017). Desmoplastic infantile
astrocytoma and ganglioglioma: Case report and review of the literature. Clinical
Neuropathology, vol. 36, no. 1, pp. 31–40.
[11] Narayan, V., Savardekar, A. R., Mahadevan, A., et al. (2017). Unusual occurrence
of multifocal desmoplastic infantile astrocytoma: A case report and review of the
literature. Pediatric Neurosurgery, vol. 52, no. 3, pp. 173–180.
