Anti bacterial activity of Psidium guajava and carthamus tinctoruis against respiratory tract infection

Yagoub   Hamadt-Allah; Nagla, M Ali; Sahar, I Mohammed; Shaza, T Mohammed

doi:10.52981/smlj.v1i2.2727

Yagoub Hamadt-Allah Faculty of medical laboratory sciences-Omdurman Islamic University, Khartoum-Sudan
Nagla, M Ali Faculty of medical laboratory sciences-Omdurman Islamic University, Khartoum-Sudan
Sahar, I Mohammed Faculty of medical laboratory sciences-Omdurman Islamic University, Khartoum-Sudan
Shaza, T Mohammed Faculty of medical laboratory sciences-Omdurman Islamic University, Khartoum-Sudan

DOI: https://doi.org/10.52981/smlj.v1i2.2727

الملخص

The aim of this study was to enrich the information about the antimicrobial activity of some medicinal plants of the Sudan. Also, to verify the claimed activity of certain Sudanese medicinal plants used in traditional medicine as antimicrobial agents, to subject these plants for further antimicrobial studies against clinical isolates, to determine their minimum inhibitory concentration (MICs) and to compare their activity with the commonly used antibacterial agents in the Sudan. The chloroform, methanol and aqueous extract of Psidium guajava leaves (family: myrtacae) and Carthaumus tinctorius seeds (family: Asterceae) were screened for their antimicrobial activity against four standard bacteria: two gram positive (Staphylococcus aureus and Streptococcus pyogenes) and two gram negative (Klebsiella pneumoniae and Pseudomonas aeruginosa) using the cup plate agar diffusion method. All six extracts were active against one or more of the four bacteria. Four of these extracts inhibited the growth of all microorganisms. Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumoniae were the most sensitive organisms to all extracts, while Streptococcus pyogenes showed less susceptibility. The antibacterial activity of five reference drugs was determined against the tested four bacteria and their activity was compared to the activity of plants extracts.

المراجع

1. Dole, C. (2004). In: The shadows of medicinal and modernity medicinal integration and secular histories of Religious healing in Turky. J. Cult. Med. Psychiatry, Vo1. 28, No. 3 255- 80.
2. Silva Junior, A.A; Vizotto, Z.J; Giorgi, E; Macedo, S.G; and Matalka, K.Z. (1994). The antimicrobial activities of Psidium guajava and Juglans regia leaf extracts to acne- developing organism. Am J chin Med 33:197-205.
3. Distasi, L.C. (1996). Arte, ciencia e magia. In LC Di Stasi CA Hiruma- Lima (eds.), J. Plantas Merdicinasis: Arte eciencia, Unesp, sao Paulo, p. 15-21.
4. Holetz, F.B; Pessini, G.L; Sanches, N.R; Cortez, D.A.G; Nakamura, C.V; and Dias filho, B.P. (2002). Screening of some plants used in the Brazilian flok medicin for the treatment of infectious diseases. J. Mem inst Oswaldo cruz 29: 1027- 1031.
5. Ghahraman, A; and Attar, F. (1998). Biological diversity of Iranian plant species. Tehran Uni. Press, Iran.
6. Almagboul, A.Z; Bahir, A.K; Salih, A.M; Farouk, A; and Khalid, S.A. (1988). Antibacterial Activity, part V. Fitoterapia, Vol. 59, No.1, 57-62.
7. Almagboul, A.Z; Farouk A; Bahir, A.K; and Salih, A.M. (1985). Antibacterial Activity of Sudanese plants used in folkloric medicine. Screening for antibacterial activity part IV. Fitoterapia, Vol.56, No.2, 103-109.
8. Ahmed, A; Khan, K.A; Ahmed, U; and Qazis U. (1986). Antimicrobial activity of Juliflorine isolated from Prosopis juliflora. J.Planta Med, No.4,285-288.
9. Abdelrahim, A.Z; Almagboul, M.E.A; Omer, A. Elegami. (2002). Antimicrobial activity of Psidium guajava L.Used inSudan.Vol.73,No.73,713-715.
10. Verma, N; Khosa, R.L; and Garg, V.K. (2008). Wound healing activity of Wedella chinensis leaves. J. Pharmacologyonline. Vol. 70, No. 3, 233-236.
11. Evans, C.E; Banso, A; and Samuel, O.A. (2002). Efficacy of some nupe medicinal plants against Salmonella typhi: an in vitro study. J. Ethnopharmacol, 80: 21-24.
12. Bae, K; and Byun, J. (1978). Screening of leaves of higher plants for antibacterial action Korean Journal Pharmacog. Vol.18, No.1, 1-4 .
13. Abd Elnabi. U.M; Reisinger, E.C; Reinthaler, F.F; Stil, F; Eibel, U; and Krejs, G.J. (1992). Antimicrobial activity of Acacia nilotica Willd. Ex del var. nilotica.J.Ethnopharmacology Vol.37, No,77-79.
14. Peters, R.G; and Plorde, J.J. (1963). The usefulness of in vitro sensitivity tests in antibiotic therapy. Ann Rev, Med. 14, 41- 56.
15. Cooper, K.E; and Kavanagh, F. (1993). Analytical Microbiology, Vol. 1. Academic Press, (Pub) New York and London.
16. Kavanagh, F. (1972) Analytical Microbiology, Vol,11, Academic Press (Pub) New York and London P 11.
17. Cruickshank, R; Duguid, J.P; Marmion Swain, R.H. (1975). Medical Microbiology. 12th Ed. Churchill Livingston, London and New York. Vol.11.
18. Blaszezyk, T; Krzyzanowska, J; and lamer zarawska, E. (2000). Screening for antimycotic properties of 56 traditional Chinese drugs. J. Phytotherapy Research, Vol. 14, No. 3, 210- 212.
19. Greenwood, D; Slack, R; and Penthere, J. (1992). Medical Microbiology. 14th Ed. Churchil, Livingstone, New York, Edinburgh, London, Madrid amd Tokyo.