An in Vitro Antimicrobial Potential of Various Extracts of Commiphora Myrrha

Abd-Ulgadir K S

Abd-Ulgadir K S

الملخص

Objectives The aim of this study was to evaluate the antimicrobial activity of various extracts obtained from the resin of medicinal plant Commiphora myrrha on standard microorganisms. Methods The agar well diffusion technique was followed to perform the antimicrobial activity of the candidate extracts against Gram-positive bacteria (Bacillus subtilis NCTC8236, Staphylococcus aureus ATCC 25923), Gram- negative bacteria (Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 53657, Proteus vulgaris ATCC6380, Pseudomonas aeruginosa ATCC 27853), as well as, two fungal species (Candida albicans ATCC 7596; Apergillus niger ATCC 9763).

Results: Methanolic and aqueous extracts of the resin of C. myrrha at concentration of 100 mg/ml was found to be more active against Gram- negative bacteria (Proteus vulgaris ATCC 6380; Klebsiella pneumoniae ATCC: 53657; Escherichia coli ATCC: 25922 and Pseudomonas aeruginosa ATCC: 27853) and Gram- positive bacteria (Bacillus subitilis NCTC: 8236), as well as, they showed high antifungal activity against (Candida albicans ATCC :7596 and Aspergillus niger ATCC:9765),while the chloroform extract of the resin showed moderate activity against Gram- positive and Gram- negative bacteria ,as well as against Candida albicans ATCC :7596,whereas the same extract revealed high antifungal activity against Aspergillus niger ATCC:9765.

Conclusion Methanolic, chloroform and aqueous extracts of the resin of C. myrrha revealed that the selected plant had a significant potential effect capable to inhibit the growth of both bacterial and fungal standard species.

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