Bacterial etiology of Community Acquired Pneumonia and their Antimicrobial Susceptibility in Patients Admitted to Alshaab Teaching Hospital

  • Ibrahim A I

الملخص

Background: Community Acquired Pneumonia (CAP) is a frequently encountered lower respiratory tract parenchymal lung infection which continues to be a major health problem leading to significant morbidity and mortality worldwide. This study was aimed to determine frequency and susceptibility pattern of bacterial etiology of community acquired pneumonia isolates from Sudanese patients.

Material and method: One hundred Sputum specimens were collected from patients with Community Acquired Pneumonia attended to chest unit in Alshaab Teaching Hospital during the period between Januarys to March 2017. The patients were grouped according their age as follows (year); 16 to 26, 27 to 37, 38 to 48, 49 to 60.Antibiotic susceptibility test of isolated organisms were carry out by the Kirby - Bauer disc diffusion method.

Result: Out of 100 patient enrolled in the study the etiology was identified in 42/100 (42%) with most frequent isolates Klebsiella pneumoniae 18/42 (42.8%) followed by: Pseudomonas aeruginosa 13/42 (30.9%), Staphylococcus aureus 10/42 (23.9%) and Escherichia coli 1/42 (2.4%). Only 3 (16.7%) organisms among all isolated klebsiella pneumoniae were found resistant to all investigated antibiotic (third generationcephalosporin (3GC)) Six6/10 (60%) from all isolated Staphylococcus aureusfound resistant to methicillin (ME10µg) and Oxicillin (OX 1µg). all isolated Pseudomonas aeruginosa were sensitive to Meropenem. The isolated Escherichia coli found only resistant to Ampicillin.

Conclusion: prevalence of community-acquired pneumonia in adult Sudanese patients is relatively high with major causative agents Klebsiella pneumoniae.

المراجع

1. Ignazio JD, Camere MA, Lewis DE, Jorgensen D, Breen JD. Novel , Single-Dose Microsphere Formulation of Azithromycin versus 7-Day Levofloxacin Therapy for Treatment of Mild to Moderate Community-Acquired Pneumonia in Adults. 2005;49(10):4035–41.
2. Almirall J, Bolíbar I, Serra-Prat M, Roig J, Hospital I, Carandell E, et al. New evidence of risk factors for community-acquired pneumonia: A population-based study. Eur Respir J. 2008;31(6):1274–84.
3. Tsolia MN, Psarras S, Bossios A, Audi H, Paldanius M, Gourgiotis D, et al. Etiology of Community-Acquired Pneumonia in Hospitalized School-Age Children : Evidence for High Prevalence of Viral Infections. 2004;2003(April 2003):9–11.
4. Restrepo MI, Anzueto A. Severe Community - Acq uire d Pneumonia. 2009;23:503–20.
5. Musher DM, Thorner AR, Europe I. Community-Acquired Pneumonia. 2014;1619–28.
6. Song J, Sup W, Kang C, Ryeon D, Ran K, Soo K, et al. Epidemiology and clinical outcomes of community-acquired pneumonia in adult patients in Asian countries : a prospective study by the Asian network for surveillance of resistant pathogens. 2008;31:107–14.
7. Pneumonia C, Metlay JP, Fine MJ. Academia and Clinic Testing Strategies in the Initial Management of Patients with. 2003;138(2):109–19.
8. Liam CK, Lim KH, Wong CM. Community-acquired pneumonia in patients requiring hospitalization. Respirology. 2001;6(3):259–64.
9. Johansson N, Kalin M, Tiveljung-lindell A, Giske CG, Hedlund J. Etiology of Community-Acquired Pneumonia : Increased Microbiological Yield with New Diagnostic Methods. 2010;50.
10. Goel N, Chaudhary U, Aggarwal R, Bala K. Antibiotic sensitivity pattern of gram negative bacilli isolated from the lower respiratory tract of ventilated patients in the Intensive care unit. Indian J Crit Care Med [Internet]. 2009;13(3):148–51. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20040812%5Cnhttp://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC2823096
منشور
2018-09-01