Evaluation of Microalbuminuria as an Early Predictor Marker of Nephropathy in Diabetic Patients in Khartoum State

Mohammed Mogtaba A

Mohammed Mogtaba A

الملخص

Background. Untreated diabetes mellitus can cause long term complications and cause chronic kidney failure or nephropathy .The aims of this study was to assess microalbumin: creatinine ratio in diabetic patients as an early predictor marker of diabetic nephropathy.

Materials and Methods. This study was conducted at Soba hospital and East of Nile hospital in Khartoum state during the period from February to May 2016. In this study 70 urine samples were collected and analyzed with full automated chemistry analyzer (COBAS C311); 35 samples from diabetic patients and 35 samples from healthy individuals as control.

Results. There was a significant increase in the mean value of microalbumin: creatinine ratio in the diabetic patients (88. 5 mg/g) compared with the mean value of microalbumin: creatinine ratio in the normal individuals (26.2 mg/g) with p-value (0.05). There was no correlation between microalbumin: creatinine ratio with age among diabetic patient, p-value (0.877).

Conclusion. From this study it was concluded that microalbumin: creatinine ratio level in diabetic patients increased and influenced by both type 2 diabetes mellitus and the duration of disease. Therefore, regular screening for microalbumin is recommended for all diabetic patients, as early diagnosis and treatment are critical for reducing cardiovascular risks and slowing the progression to late stages of diabetic nephropathy.

المراجع

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