Assessment of Antibiotics prescription in Hospitalized Patients at Elobeid Hospital, Sudan
الملخص
Objective: This study aimed to assess the pattern of antibiotics usage in medical wards at Elobeid
teaching hospital, West Sudan.
Patients and method: This is a descriptive hospital-based study. The data were retrospectively
collected from the patient’s records. Systemic random sampling was used to select 427 patient’s
records from the records of patients who were admitted to the medical wards in the year 2008. The
records of 250 patients showed antibiotic prescription constituting 58.5% of the selected records.
Beside the sociodemographic data, drug data (drug name, drug strength, route of administration and
duration of therapy), basis of prescription (empirical or definitive) and other relevant information
were collected from the patient’s records and analyzed.
Results: A total of 427 patient’s records were selected for the study, out of which 250 (58.5%) for
whom one or more antibiotic was prescribed were studied. Males were 60% of the patients. The
mean age ± SD of the patients was 50 ± 21 years. The total number of prescribed antibiotics was
397 drugs. Cephalosporins constituted more than one third (34.5%) of the prescribed antibiotics,
and penicillins 28.5%. The mean number of antibiotic ±SD prescribed for each patient was 1.6 ±
o.95 drugs. 148 (37.2%) of the drugs were prescribed in generic name. In 52 (13%) drug
prescriptions, the drug strength was not written. In the majority of the records (92.9%), the duration
of drug therapy was not stated. Parenteral route of drug administration was prescribed for 50.8% of
the antibiotics. The most commonly prescribed antibiotics were ceftriaxone, amoxycillin-clavulanic
acid combination, benzyl penicillin (penicillin G), ciprofloxacin, cefuroxime, and metronidazole.
Conclusion: The empirical prescription of antibiotics is a common practice at Elobeid Teaching
Hospital; therefore establishment of antibiotics guideline based on local epidemiological data of
potential pathogens and their pattern of antibiotics susceptibility should be available.
المراجع
French GL. Clinical impact and relevance of antibiotic resistance. Adv Drug Deliv Rev 2005; 57: 1514-27.
The rational use of drugs: report of the conference of experts. Geneva, World Health Organization, 1985.
Promoting rational use of medicines: core components. WHO policy perspectives on medicines. Geneva, World Health Organization, 2002 (WHO/EDM/2002.3).
Ibeawuchi R, Mbata T. Rational and irrational use of antibiotics. Africa Health, 2002; 24(2): 16-8.
Kulkarni RA, Kochhar PH, Dargude VA et al. Patterns of antimicrobial use by surgeons in India. Ind J Surg 2005;67:308-15.
Uzun O, Guven G.S. Principles of good use of antibiotics in hospitals. Journal of hospital infection 2003; 53(2): 91-96.
Gaash B. Irrational use of Antibiotics. Indian Journal for the prescribing Doctor; 2008; 5(1): 56-59.
Al-Niemat S.I, Blourkh D.T, Al-Harasis M.D et al. Drug use evaluation of antibiotics prescribed in a Jordian hospital outpatient and emergency clinics using WHO prescribing indicators. Saudi Med J 2008; 29 (5): 743-748.
Akande T.M, Ologe M, Medubi G.F. Antibiotic prescription pattern and cost at University of Ilorin teaching hospital, Ilorin, Nigeria. International Journal of Tropical Medicine 2009; 4(2): 50-54.
